Marcellino Rudyanto, Drs., Apt., MSi., PhD

Profiles

• Sinta Profile
• Scopus Profile

Courses

Organic Chemistry I, Organic Chemistry II, Synthetic Chemistry, Introduction to Drug Synthesis, Drug Synthesis, Spectroscopic Identification of Organic Compounds, Pharmaceutical Polymer.

Research Interests

• Synthesis of biologically active compounds
• Development of synthetic methodology
• Drug development

Selected Publications

1. In vivo anticancer activity of benzoxazine and aminomethyl compounds derived from eugenol; Journal of Public Health in Africa; 2023
2. Synthesis and anticancer evaluation of N-benzoyl-N'-phenyltiourea derivatives against human breast cancer cells (T47D); Journal of Chinese Pharmaceutical Sciences; 2020
3. Larvicidal Activity and Histopathological Effect of Averrhoa bilimbi Fruit Extract on Aedes aegypti from Surabaya, Indonesia; Journal of Parasitology Research; 2020
4. In vivo biomaterial study of collagen-chitosan-sodium hyaluronate composite as artificial cornea; Journal of International Dental and Medical Research; 2020
5. A prospective modification structure: The effect of lipophilic and electronic properties of n-(phenylcarbamothyoil)benzamide derivatives on cytotoxic activity by in silico and in vitro assay with t47d cells; Rasayan Journal of Chemistry; 2020
6. Dini Kesuma, Siswandono, Bambang Tri Purwanto, Marcellino Rudyanto. 2018. SynthesisofN-(phenylcarbamothioyl)-benzamide derivatives and their cytotoxic activity against MCF-7 cells J. Chin. Pharm. Sci. 27(10), 665-671. https://www.jcps.ac.cn/fileup/HTML/1003-1057(2018)10-696-07.shtml
7. Dini Kesuma, Siswandono, Bambang Tri Purwanto, Marcellino Rudyanto. 2018. Docking, Synthesis and Cytotoxic Test on Human Breast Cancer Cell Line T47D of N-(Phenylcarbamothiioyl)-Benzamide..World J. Pharm. Res., 7(7), 70-78. https://wjpr.net/dashboard/archive_show/2018/VOLUME%207,%20APRIL%20ISSUE%207
8. Alvan F. Shalas, Siswandono, Marcellino Rudyanto. 2018. Synthesis and Pain Inhibition Activity of the Analogs of 1-Allyl-3-Benzoylthiourea for New Analgesic Lead Compound Discovery. J. Young Pharm., 10(1), 12-15. https://www.jyoungpharm.org/article/1082
9. Alvan F. Shalas, Siswandono, Marcellino Rudyanto. 2016. Synthesis and Structure-Activity Relationship of 1-Allyl-3-(2-Chlorobenzoyl)-thiourea as Analgesic. Int. J. Pharm. Pharm. Sci. 8(6), 297-298. https://innovareacademics.in/journals/index.php/ijpps/article/view/11184
10. Marcellino Rudyanto, Tri Widiandani, Achmad Syahrani. 2015. Benzoxazine and Aminomethyl Derivatives of Eugenol: Cytotoxicity on MCF-7 Cell Line. Int. J. Pharm. Pharm. Sci. 7(5), 229-232. https://innovareacademics.in/journals/index.php/ijpps/article/view/4109
11. Marcellino Rudyanto, Juni Ekowati, Tri Widiandani, Toshio Honda. 2014. Synthesis and Brine Shrimp Lethality Test of Some Benzoxazine and Aminomethyl Derivatives of Eugenol. Int. J. Pharm. Pharm. Sci. 6(2), 96-98. https://innovareacademics.in/journal/ijpps/Vol6Issue2/8467.pdf
12. Marcellino Rudyanto, Koichi Kobayashi, Toshio Honda. 2009. Synthetic Studies on Isocoumarins and Isocarbostyril Derivatives Having an Alkyl Substituent at the 3-Position: Total Syntesis of Scoparines A and B. Heterocycles 79, 753-764. https://www.heterocycles.jp/newlibrary/libraries/journal/79/1/page:3
13. Marcellino Rudyanto, Yuichiro Tomizawa. Hiroshi Morita, Toshio Honda. 2008. First Total Synthesis of Cassiarin A. Organic Letters 10, 1921-1922. https://pubs.acs.org/doi/10.1021/ol8004112
14. Shiori Oshimi, Yuichiro Tomizawa, Yusuke Hirasawa, Toshio Honda, Wiwied Ekasari, Aty Widyawaruyanti, Marcellino Rudyanto, Gunawan Indrayanto, Noor Cholies Zaini, Hiroshi Morita. 2008. Chrobisiamone A, a New Bischromone from Cassia siamea and a Biomimetic Transformation of 5-Acetonyl-7-hydroxy-2-methylchromone into Cassiarin A. Bioorg. Med. Chem. Lett. 18, 3761-3763. https://www.sciencedirect.com/science/article/pii/S0960894X08005398?via%3Dihub
15. Marcellino Rudyanto, Natsuko Kagawa, Masahiro Toyota, Masataka Ihara, 2002. A Concise Synthesis of A Potential Key Intermediate for 12-Epi-Mycalamide A. Heterocycles 58, 655-658. https://www.heterocycles.jp/newlibrary/libraries/journal/58/1/hetero44@pharm.hokudai.ac.jp/page:3
16. Masahiro Toyota, Marcellino Rudyanto, Masatakan Ihara. 2002. Some Aspects of Palladium-Catalyzed Cycloalkenylation: Developments of Environmentally Benign Catalytic Conditions and Demonstration of Tandem Cycloalkenylation. J. Org. Chem. 67, 3374-3386. https://pubs.acs.org/toc/joceah/67/10
17. Masahiro Toyota, Marcellino Rudyanto, Masatakan Ihara. 2000. Application of palladium-catalyzed cycloalkenylation reaction to terpenoid synthesis – novel approach to tricyclo[5.3.1.02,6]-undecane derivative and its transformation into tricyclo[5.3.1]undecane ring system.. Tetrahedron Lett. 41, 8929-8932. https://www.sciencedirect.com/journal/tetrahedron-letters/vol/41/issue/46

Contact

Marcellino Rudyanto, Drs., Apt., MSi., PhD

E-mail instansi marcellino-r@ff.unair.ac.id