Dr. Juni Ekowati, M.Si.,Apt

 

Year

Education

1990

Bachelor of Science, Dra., Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Universitas Airlangga, Indonesia

1991

Apothecary, Apt, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Universitas Airlangga, Indonesia

1997

Master of Science, MSi., Faculty of Pharmacy, Universitas Airlangga, Indonesia

2012 

Doctor, Dr, Faculty of Science and Technology, Universitas Airlangga, Indonesia

 

Courses

Organic Chemistry, Physical Organic Chemistry, Basic Physics, Basic Chemistry, Pharmaceutical Synthesis, Natural Organic Chemistry. 

 

Research Interests

• Development of natural sources for drug candidate
• Investigations of bioactive compounds by organic synthesis and semi synthesis reaction
• Applications of in silico modelling to Drug design
• Development synthesis method of drug candidate
• Bioassay of cancer chemoprevention, anticancer, analgesic, antiangiogenesis, antiplatelet activity

 

Selected Publications

  1. Juni Ekowati, Nuzul Wahyuning Diyah, Achmad Syahrani. 2019. Synthesis and Antiplatelet Activities of Some Derivatives of p-Coumaric Acid, Chem. Chem. Technol., 13(3), 296-302. DOI:10.23939/chcht13.03.296. https://www.researchgate.net/publication/334467428_Synthesis_and_Antiplatelet_Activites_of_Some_Derivatives_of_p-Coumaric_Acid

  2. Juni Ekowati, Iwan Syahrial Hamid, Kholis Amalia Nofianti, Shigeru Sasaki. 2019. Synthesis of Thiourea Derivatives from m-Methoxycinnamic Acid as Antiangiogenic Candidate, Jurnal Teknologi, 81(4) , 105–114 | www.jurnalteknologi.utm.my | eISSN 2180–3722 |DOI: https://doi.org/10.11113/jt.v81.13410| https://jurnalteknologi.utm.my/index.php/jurnalteknologi/article/view/13410

  3. Juni EkowatiFerulic Acid Prevents Angiogenesis Through Cyclooxygenase-2 and Vascular Endothelial Growth Factor on The Chick Embryo Chorioallantoic Membrane Model, TJPS, 2020(in process to publish) DOI: 10.4274/tjps.galenos.2019.44712. http://www.turkjps.org/archives/archive-detail?vid=2326

  4. Idha Kusumawati, KO Kurniawan, S Rulliansyah, TA Prijo, Retno Widyowati, Juni Ekowati, EP Hestianah, Suprapto Maat, K Matsunami. 2018. Anti-aging properties of Curcuma heyneana Valeton & Zipj: A scientific approach to its use in Javanese tradition, Journal of Ethnopharmacology, 225:64-70. doi: 10.1016/j.jep.2018.06.038 https://www.ncbi.nlm.nih.gov/pubmed/30008394.

  5. Rizki Amalia Adlina Affandhi, Juni Ekowati, Noor Erma Nasution. 2018. Extraction, Isolation and Analysis of Chondroitin Sulphate from Chicken Shank by Spectrophotometric Method, Research J. Pharm. and Tech, 11(12) :5327. DOI: 10.5958/0974-360X.2018.00969.1 https://www.researchgate.net/publication/333187485_Extraction_Isolation_and_Analysis_of_Chondroitin_Sulphate_from_Chicken_Shank_by_Spectrophotometric_Method

  6. Juni Ekowati, Nuzul Wahyuning Diyah, Kholis Amalia Nofianti, Iwan Sahrial Hamid, Siswandono. 2018. Molecular Docking of Ferulic Acid Derivatives on P2Y12 Receptor and their ADMET Prediction, Journal Mathematical and Fundamental Sciences, 50(2), 203-219. ISSN: 2337-5760, DOI: 10.5614/j.math.fund.sci.2018.50.2.8 http://journals.itb.ac.id/index.php/jmfs/article/view/6448/3295

  7. Tanaya Djati Dharma Dewi, Juni Ekowati. 2017. Design, Synthesis and Analgesic Activity of 3-ChlorobenzoylN-(2-amino-4-chlorophenyl) anthranilic acid, International Journal of Pharmaceutical Chemistry, 07(12), 162-166. https://ssjournals.com/index.php/ijpc/article/view/4618/3136

  8. Juni Ekowati, Retno Widyowati, Dewi Isadiartuti. 2017. Preparation of an inclusion complex system of ethyl p-methoxycinnamate -hydroxypropyl-β-cyclodextrin: Characterization and solubility evaluation, Research Journal of Pharmaceutical, Biological and Chemical Sciences, 8(1), 1486-1494.https://www.rjpbcs.com/pdf/2017_8(1)/[186].pdf

  9. Galih Satrio Putra, Anita Puspa Widiyana, Luthfi Ahmad Muchlashi, Mellany Ika Sulistyowaty, Juni Ekowatiand Tutuk Budiati. 2017. The influence of ratio pyridine and triethylamine catalysts on synthesis 2-Phenyl-Benzo[D] [1,3] Oxazine-4-on derivatives, Journal of Chemical and Pharmaceutical Research, 9(8),73-80. http://www.jocpr.com/articles/the-influence-of-ratio-pyridine-and-triethylamine-catalysts-on-synthesis-2phenylbenzod-13-oxazine4on-derivatives.pdf

  10. Galih Satrio Putra, Melanny Ika Sulistyowati, Juni Ekowati, Tutuk Budiati. 2017. Molecular modelling and in silico analysis of p-methoxycinnamoyl hydrazide analogues as Checkpoint Kinase-1 and aromatase inhibitors, Pharm Sci Res, 4(2), 66-80. https://www.researchgate.net/publication/319706783_Pemodelan_Molekul_Turunan_p-Metoksi_sinnamoil_Hidrazida_Sebagai_Inhibitor_Checkpoint_Kinase_1_dan_Inhibitor_Aromatase_secara_In_silico

  11. Juni Ekowati, Septri D Rahman, Dewi Isadiartuti, Retno Widyowati, Tutuk Budiati. 2016. Synthesis of Ferulic Acid and Its Non Covalent Inclusion with Hydroxypropyl-b-cyclodextrin, IJPCR, 8(3), 198-205. https://ijpcr.com/volume8issue3/.

  12. Melanny Ika Sulistyowati, AE Nugroho, Galih S Putra, Juni Ekowati, Tutuk Budiati. 2016. Syntheses, Molecular Docking Study and Anticancer Activity Examination of p-Methoxycinnamoyl Hydrazides, IJPCR, 8(6), 623-627. https://www.ijpcr.com.

  13. Melanny Ika Sulistyowati, Kholis Amalia Nofianti, Juni Ekowati, Galih S Putra, Tri Widiandani, Tutuk Budiati. 2015. Antibacterial and Antioxidant Activity Evaluation of 1, 3-Diaryl-prop-2-en-1-one Derivatives. Procedia Chemistry, 16, 372-375. https://www.sciencedirect.com/science/article/pii/S1876619615002144

  14. Juni Ekowati, Suko Hardjono, Iwan Sahrial Hamid. 2015. Ethyl p-methoxycinnamate from Kaempferia galangal inhibits angiogenesis through tyrosine kinase, Universa Medicina, 34(1),43-51. DOI: http://dx.doi.org/10.18051/UnivMed.2015.v34.43-51. https://univmed.org/ejurnal/index.php/medicina/article/view/49

  15. Nuzul Wahyuning Diyah, Juni Ekowati, Siswandono. 2014. Synthesis and Antitumor Activity Evaluation of N,N’-dibenzoyl-N,N’-diethylurea against Human Breast Cancer Cell Line (MCF-7), IJPPS, 6(2), 315-318. https://innovareacademics.in/journal/ijpps/Vol6Issue2/8812.pdf

  16. Marcellino Rudyanto, Juni Ekowati, Tri Widiandani, Toshio Honda. 2014. Synthesis and Brine Shrimp Lethality Test of Some Benzoxazine and Aminomethyl Derivatives of Eugenol. IJPPS, 6(2), 96-98. https://innovareacademics.in/journals/index.php/ijpps/article/view/4109

  17. Juni Ekowati, Nur Chaulah, Tutuk Budiati. 2014. Sintesis dan Uji in silico Turunan Asam Fenilpropanoat sebagai Anti platelet. Berkala Ilmiah Kimia Farmasi, 3(2), 44-50. https://www.semanticscholar.org/paper/SINTESIS-DAN-UJI-IN-SILICO-TURUNAN-ASAM-SEBAGAI-Ekowati-Chaulah/de15f6fc97a7a43630777ce0697aba94a34ddcca.

  18. Juni Ekowati& Nuzul Wahyuning Diyah. 2013. Aktivitas Antinociceptive dan Uji In Silico terhadap Cyclooxygenase dari Asam p-metoksisinamat dan Asam m-metoksisinamat. Berkala Ilmiah Kimia Farmasi, 2(1), 33-40. https://pdfs.semanticscholar.org/91de/5779311fe63a7ec5e23f950f255c1d511299.pd

  19. Juni Ekowati, Bimo A. Tedjo, Shigeru Sasaki, Kimio Highasiyama, Sukardiman, Siswandono, Tutuk Budiati. 2012. Structure Modification of Ethyl p-methoxycinnamate and Their Bioassay as Chemopreventive Agent Against Mice’s Fibrosarcoma, IJPPS, 3 (suppl.4), 528-532. https://pdfs.semanticscholar.org/0926/554e1b03b41914387f3b2d4512b6198b6d6b.pdf

 

Contact

Dr. Juni Ekowati, M.Si.,Apt

E-mail  j_ekowati@yahoo.com

E-mail Instansi  juni-e@ff.unair.ac.id 


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