Dr. Idha Kusumawati, M.Si.,Apt

Profiles

• Sinta Profile
• Scopus Profile

Courses

Pharmaceutical Botany, Pharmacognosy, Phytochemistry, Phytopharmacy, Pharmaceutical Manufactures I (PBL)

Research Interests

• Herbal Drug Development (Anti-aging, Analgesic-Antiinflammatory, Afrodisiac,
• Immunomodulator, Photosensitisizer, Woundhealing, Psoriasis)
• Drug Delivery System of Herbal Extract
• Analytical Development of Marker compound of Herbal Extract
• Preclinical Study of Herbal Extract
• Metabolite Profilling
• Multivariate Analysis and Design Experimental

Selected Publications

1. Influence of the Environment on Biofilm Formation Candida albicans of Vulvovaginal Candidiasis Isolate Patient; Pharmacognosy Journal; 2023

2. ACUTE TOXICITY ASSESSMENT OF GRAPTOPHYLLUM PICTUM (L.) GRIFF. LEAVES ETHANOLIC EXTRACT AND ITS NANOFORMULATIONS: COMPARATIVE STUDY OF PHYTOSOME AND CYCLODEXTRIN INCLUSION COMPLEX; Farmacia; 2023

3. A SYSTEMATIC REVIEW OF POTENTIAL PHYTOCHEMICAL COMPOUND BARK OF PARAMERIA LAEVIGATA ON BIOFILM FORMATION; International Journal of Applied Pharmaceutics; 2022

4. Histomorphometric study of ethanolic extract of Graptophyllum pictum (L.) Griff. leaves on croton oil-induced hemorrhoid mice: A Javanese traditional anti-hemorrhoid herb; Journal of Ethnopharmacology; 2022

5. Assessment of Topical and Transdermal Penetration of Curcuma heyneana Rhizome Extract in Rat Skin: Histological Analysis; Series Methods in Molecular Biology; 2022

6. A Great Challenge on the Reproducibility of Therapeutic Results of Phytopharmaceuticals; Phytopharmaceuticals: Potential Therapeutic Applications; 2021

7. Combination of curcumin photosensitizer with laser diode to reduce antibiotic resistant bacterial biofilms; Malaysian Journal of Medicine and Health Sciences; 2021

8. Bisindole alkaloids from Voacanga grandifolia leaves; Journal of Natural Medicines; 2021

9. Effectiveness of photodynamic inactivation with exogenous photosensitizer curcuma longa extract activated by laser diode 403 nm on staphylococcus aureus; Journal of International Dental and Medical Research; 2020

10. Histomorphometric Analysis of Anti-Aging Properties on Rat Skin; Series Methods in Molecular Biology; 2020

11. Isnaeni, Agustin Maulidina, Idha Kusumawati, Erni Maduratna S. 2019. Inhibitory activity of Lactobacillus plantarum ATCC 8014 fermented milk combined with aqueous extract of Moringa oleifera leaves against Streptococcus mutans, J. Research in Pharmacy/Marmara. Vol 23 (4), ISSN: 2630-6344
    https://jrespharm.com/uploads/pdf/pdf_MPJ_718.pdf

12. Idha Kusumawati, Kresma Oky Kurniawan, Subhan Rullyansyah, Tri Anggono Prijo, Retno Widyowati, Juni Ekowati, Eka Pramyrtha Hestianah, Suprapto Maat, Katsuyoshi Matsunami, 2018, Anti-aging Properties of Curcuma heyneana Valeton & Zipj: A Scientific Approach to Its Use in Javanese Tradition, Journal of Ethnopharmacology, 225, 64 – 70, ISSN: 0378-8741 in https://www.sciencedirect.com/science/article/pii/S0378874118305221?via%3Dihub

13. Mangestuti Agil, Idha Kusumawati, and Neny Purwitasari, 2017, Phenotypic Variation Profile of Marsilea crenata Presl. Cultivated in Water and in the Soil Journal of Botany, Volume 2017, Article ID 7232171, 6 pages https://www.hindawi.com/journals/jb/2017/7232171/abs/

14. Hariyadi, Dewi Melani; Hendradi, Esti; Kusumawati, Idha; Azzahra, Fauzia, 2017, Histopathology Study Of Alginate Microspheres Containing Ovalbumin On Liver And Kidney Following Oral Administration And Evaluation Of Uptake By Peyer's Plaque, Turkish Journal Of Pharmaceutical Sciences, Vol. 14 Issue 3, P243-250.
    https://web.a.ebscohost.com/abstract?direct=true&profile=ehost&scope=site&authtype=crawler&jrnl=1304530X&AN=126373349&h=pzysjgYNYwdRMbH6rAtzT9d1v%2fum5v%2b4T0xx8K5KzwSdLiUhKB05TxsO20GOTnQO36yMF1A2jZGLDW0y4mt%2fNQ%3d%3d&crl=c&resultNs=AdminWebAuth&resultLocal=ErrCrlNotAuth&crlhashurl=login.aspx%3fdirect%3dtrue%26profile%3dehost%26scope%3dsite%26authtype%3dcrawler%26jrnl%3d1304530X%26AN%3d126373349

15. Hariyadi, D.M., Purwanti, T., Kusumawati, I., Nirmala, R.N., Maindra, H.M.C., 2015, Physical Characterization and In Vivo Study of Ovalbumin Encapsulated in Alginate Microspheres International Journal of Drug Delivery Technology; 5(2); 48-53 ISSN: 0975-4415 https://ijddt.com/volume5issue2/

16. Azusa Haseo, Alfarius Eko Nugroho, Yusuke Hirasawa, Toshio Kaneda, Osamu Shirota, Abdul Rahman, Idha Kusumawati, Noor Cholies Zaini, and Hiroshi Morita, 2015, A New Indole Alkaloid from Voacanga grandifolia Heterocycles Special issue | Vol 90, No. 1, , pp. 601 - 606 ISSN: 1881-0942 https://www.heterocycles.jp/newlibrary/libraries/journal/90/1/page:2

17. Jun Deguchi, Tadahiro sasaki, Yusuke Hirasawa, Toshio Kaneda, Idha Kusumawati, Osamu Shirota, Hiroshi Morita, 2014, Two novel tetracycles, cassibiphenols A and B from the flowers of Cassia siamea Tetrahedron Letters Vol 55, Issue 7, pp. 1362-1365 ISSN: 0040-4039
    https://www.sciencedirect.com/science/article/pii/S004040391400046X

18. Sugiyartono, Dike Bagus Pamuji, Agil Antono,Idha Kusumawati, Isnaeni, 2014, Physical Characteristic And Viability Of Lactobacillus Acidophillus Microparticle Using Hpmc K100lv And Hpmc K4m As Matrices, Int J Pharm Pharm Sci, Vol 6, Suppl 2, 296-298, ISSN- 0975-1491, https://innovareacademics.in/journal/ijpps/Vol6Suppl2/8300.pdf

19. Yuta Nagakura, Alfarius Eko Nugroho, Yusuke Hirasawa, Takahiro Hosoya, Abdul Rahman, Idha Kusumawati, Noor Cholies Zaini, Hiroshi Morita, 2013, Sanjecumins A and B: new limonoids from Sandoricum koetjape J Nat Med 67:381–385 ISSN: 1861-0293
    https://pdfslide.net/documents/sanjecumins-a-and-b-new-limonoids-from-sandoricum.html

20. Yusuke Hirasawa, Hiroko Arai, Abdul Rahman, Idha Kusumawati, Noor Cholies Zaini, Osamu Shirota, Hiroshi Morita, 2013, Voacalgines AeE, new indole alkaloids from Voacanga grandifolia, Tetrahedron 69, 10869e10875, ISSN: 0040-4020
    https://www.sciencedirect.com/science/article/pii/S0040402013017262

21. Idha Kusumawati, Gunawan Indrayanto, 2013, Atta-ur-Rahman (Ed) Studies in Natural Products Chemistry Vol. 40: Chapter 15. Natural Antioxidants in Cosmetics, Elsevier B.V., ISSN: 1572-5995
    https://books.google.co.id/books?id=vYV1DAAAQBAJ&pg=PT1&lpg=PT1&dq=chapter+15+-+natural+antioxidants+in+cosmetics&source=bl&ots=pghsPRequV&sig=ACfU3U2HJu7HB2wvli8ipR_H8UdC288edA&hl=en&sa=X&ved=2ahUKEwiijKia2tfjAhUt7XMBHd9OBfwQ6AEwBHoECAgQAQ#v=onepage&q=chapter%2015%20-%20natural%20antioxidants%20in%20cosmetics&f=false

22. Hiroko Arai, Kazumasa Zaima, Erika Mitsuta, Haruka Tamamoto, Aiko Saito, Yusuke Hirasawa, Abdul Rahman, Idha Kusumawati, Noor Cholies Zaini, Hiroshi Morita, 2012, Alstiphyllanines I–O, ajmaline type alkaloids from Alstonia macrophylla showing vasorelaxant activity, Bioorganic & Medicinal Chemistry 20, pp. 3454–3459, ISSN: 0968-0896,
    https://www.sciencedirect.com/journal/bioorganic-and-medicinal-chemistry/vol/20/issue/11

23. Takahiro Hosoya, Fumie Yamasaki, Asami Nakata, Abdul Rahman, Idha Kusumawati, Noor Cholies Zaini, Hiroshi Morita, 2011, Inhibitors of Nitric Oxide Production from Stemona javanica, Planta Medica; 77: 256–258, ISSN 0032‐0943,
    https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0030-1250383

24. Idha Kusumawati and Helmy Yusuf, 2011, Phospholipid Complex as A Carrier Of Kaempferia Galanga Rhizome Extract To Improve Its Analgesic Activity, International Journal of Pharmacy and Pharmaceutical Sciences Vol 3, Suppl 1, pp.44-46, ISSN- 0975-1491,
    https://innovareacademics.in/journal/ijpps/Vol3Suppl1/12.pdf

25. Adil Astulla, Yusuke Hirasawa, Abdul Rahman, Idha Kusumawati, Wiwied Ekasari, Aty Widyawaruyanti, Noor Cholies Zaini and Hiroshi Morita, 2011, Melidianolic Acid A and B, New Antimalarial Acyclic Diterpenes from Aphanamixis grandifolia, Natural Product Communications Vol. 6 (3) pp. 323-326, ISSN: 1934578X,
    https://www.sciencedirect.com/science/article/pii/S0040402013017262https://www.sciencedirect.com/science/article/pii/S0040402013017262

26. Hiroko Arai, Yusuke Hirasawa, Abdul Rahman, Idha Kusumawati, Noor Cholies Zaini, Seizo Sato, Chihiro Aoyama, Jiro Takeo and Hiroshi Morita, 2010, Alstiphyllanines E–H, picraline and ajmaline-type alkaloids from Alstonia macrophylla inhibiting sodium glucose cotransporter, Bioorganic & Medicinal Chemistry 18, pp. 2152–2158, ISSN: 0968-0896 https://www.sciencedirect.com/journal/bioorganic-and-medicinal-chemistry/vol/18/issue/6

27. Yuta Nagakura, Reiko Yamanaka, Yusuke Hirasawa, Takahiro Hosoya, Abdul Rahman, Idha Kusumawati, Noor Cholies Zaini and Hiroshi Morita, 2010, Gaudichaudysolin A, A New Limonoid From The Bark Of Dysoxylum Gaudichaudianum, Heterocycles, Vol. 80, No. 2, pp. 1471 - 1477. ISSN: 1881-0942,
    https://www.heterocycles.jp/newlibrary/libraries/journal/80/2/page:3

28. Yusuke Hirasawa, Saori Miyama, Takahiro Hosoya,, Koichiro Koyama, Abdul Rahman, Idha Kusumawati,, Noor Cholies Zaini,, Hiroshi Morita, 2009, Alasmontamine A, A First Tetrakis Monoterpene Indole Alkaloid from Tabernaemontana elegans, Organic Letter Volume 11, Issue 24, p 5718-5721, ISSN: 1523-7052,
    https://pubs.acs.org/doi/abs/10.1021/ol902420s

29. Kazumasa Zaima, Tomoko Hirata, Takahiro Hosoya, Yusuke Hirasawa, Koichiro Koyama, Abdul Rahman, Idha Kusumawati, Noor Cholies Zaini, Mooto Shiro, Hiroshi Morita, 2009, Biscarpamontamines A and B, an Aspidosperma −Iboga Bisindole Alkaloid and an Aspidosperma −Aspidosperma Bisindole Alkaloid, from Tabernaemontana sphaerocarpa, Journal of Natural Product Volume 72, Issue 9, pp. 1686–1690, ISSN: 1520-6025 in https://pubs.acs.org/doi/abs/10.1021/np900365r

30. Kusumawati, I., Rullyansyah, S., Rohmania, Rizka, A. F., Hestianah, E. P., & Matsunami, K. (2022). Histomorphometric study of ethanolic extract of Graptophyllum pictum (L.) Griff. leaves on croton oil-induced hemorrhoid mice: A Javanese traditional anti-hemorrhoid herb. Journal of Ethnopharmacology, 284, 114765. https://doi.org/10.1016/j.jep.2021.114765
31. Kusumawati, I., Rohmania, Warsito, M. F., & Hestianah, E. P. (2022). Assessment of Topical and Transdermal Penetration of Curcuma heyneana Rhizome Extract in Rat Skin: Histological Analysis. Methods in Molecular Biology (Clifton, N.J.), 2343, 299–307. https://doi.org/10.1007/978-1-0716-1558-4_21
32. Anggraini, W., Purwanto, D. A., Isnaeni, Kusumawati, I., & Suryanto (2022). A Systematic Review Of Potential Phytochemical Compound Bark Of Parameria Laevigata On Biofilm Formation. International Journal of Applied Pharmaceutics, 14(Special Issue 1), 21- 26. https://doi.org/10.22159/ijap.2022.v14s1.05

Contact

Dr. Idha Kusumawati, M.Si.,Apt

E-mail idhakusumawati.unair@gmail.com

E-mail Instansi idha-k@ff.unair.ac.id