Prof. apt. Dewi Melani Hariyadi, SSi, MPhil, PhD

Courses

Pharmaceutical Liquid Dosage Forms, Pharmaceutical Semisolid Dosage Forms, Radiopharmaceuticals, Drug Delivery System, Advanced Delivery System, Targeted Delivery System and Inhalation Delivery System

Research Interests

• Investigations of microspheres and nanospheres using natural and synthetic polymers
• Drug, protein and vaccine delivery systems for oral, pulmonary and topical applications
• Development of natural sources for topical microspheres

Selected Publications

1. Dewi Melani Hariyadi, Sharon Lin, Yiwei Wang, Thor Bostrom, Mark S. Turner, Bhesh Bhandari, Allan GA Coombes, 2010, Diffusion Loading and Drug Delivery Characteristics of Alginate Gel Microparticles Produced by A Novel Impinging Aerosols Method, Journal of Drug Targeting, ISSN:1061-186X; 18 (10) 831-841. https://www.ncbi.nlm.nih.gov/pubmed/20958098
2. Dewi Melani Hariyadi, Thor Bostrom, Bhesh Bhandari, Allan GA Coombes, 2012, A Novel Impinging Aerosols Method for Production of Propranolol Hydrochloride-Loaded Alginate Gel Microspheres for Oral Delivery, Journal of Microencapsulation, ISSN 0265-2048; 29 (1) 63-71. https://www.ncbi.nlm.nih.gov/pubmed/22185434
3. Dewi Melani Hariyadi, Sharon Lin, Yiwei Wang, Thor Bostrom, Bhesh Bhandari, Allan GA Coombes, 2012, Novel alginate gel microspheres produced by impinging aerosols for oral delivery of proteins, Journal of Microencapsulation, ISSN 0265-2048; 29 (3) 25-261. https://www.tandfonline.com/doi/abs/10.3109/02652048.2011.646329
4. Dewi Melani Hariyadi, Yiming Ma, Yiwei Wang, Thor Bostrom, Jacob Malouf, Mark S. Turner, Bhesh Bhandari, Allan GA Coombes, 2014, The potential for production of freeze-dried oral vaccines using alginate hydrogel microspheres as protein carriers, Journal of Drug Delivery Science and Technology, ISSN 1773-2247; 24 (2) 178-184. https://www.sciencedirect.com/science/article/pii/S1773224714500299
5. Dewi Melani Hariyadi, Esti Hendradi, Tutiek Purwanti, Farah Diba Genie Permana Fadil, Chandra Nourmasari Ramadani, 2014, Effect of Crosslinking Agent and Polymer on The Characteristics of Ovalbumin-Loaded Alginate Microspheres, International Journal of Pharmacy and Pharmaceutical Sciences, ISSN 0975-1491, 6(4), 469-474. https://www.scopus.com/inward/record.uri?eid=2-s2.0-84899862019&partnerID=40&md5=31bc61f304a4c4fa0330b7f0c5bbe7e7
6. Dewi Melani Hariyadi, Tutiek Purwanti, Idha Kusumawati, Rahma Nita Nirmala, Halib Masbubi Cipta Maindra, 2015, Physical Characterization and In Vivo Study of Ovalbumin Encapsulated in Alginate Microspheres, International Journal of Drug Delivery Technology, ISSN:0975-4415 ; 2015;5(2); 48-53. https://www.scopus.com/inward/record.uri?eid=2-s2.0-84928266542&partnerID=40&md5=9eab09118f3f482a69c320706acfe7ec
7. Dewi Melani Hariyadi, Tutiek Purwanti, Destia Wardani, 2016, Stability of Freeze-Dried Ovalbumin-Alginate Microspheres with Different Lyoprotectants, Research Journal of Pharmaceutical Technology, ISSN:0974-360X ; 2016; 9(1); 119-125. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85045215680&doi=10.5958%2f0974-360X.2016.00005.6&partnerID=40&md5=0e9d407cdcff3128ffd864e6c6e9a180
8. Dewi Melani Hariyadi, Esti Hendradi, Idha Kusumawati, Halib Masbubi Cipta Maindra, Fauziah Azzahra, 2016, Evaluation of The Antibody Response And Uptake of Ca-Alginate Microspheres Containing Model Antigen After Oral Immunization, International Journal of Pharmaceutical and Clinical Research, ISSN:0975-1556 ; 2016; 8(2); 151-157. https://www.scopus.com/inward/record.uri?eid=2-s2.0-84961252226&partnerID=40&md5=f046136e5c69df09552095d898369a0f
9. Widyaningrum I., Dewi Melani Hariyadi, Hendradi E., 2017, Anti-Inflammatory Evaluation of NLC (Nanostructured Lipid Carriers) Meloxicam In-Vivo, International Journal of Drug Delivery Technology, ISSN 09754415; 7(4), 327-331. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85040048945&partnerID=40&md5=847671974cfe0cad172eb4978057712f
10. Dewi Melani Hariyadi, Esti Hendradi, Idha Kusumawati, Fauzia Azzahra, 2017, Histopathology Study of Alginate Microspheres Containing Ovalbumin on Liver and Kidney Following Oral Administration and Evaluation of Uptake by Peyer’s Plaque, Turk J Pharm Sci, ISSN 1304530X; 14(3), 243-250. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85035073402&doi=10.4274%2ftjps.93585&partnerID=40&md5=195e6181527b4e2ab73ff65b7b03c24f
11. Fitria Nugrahaeni, Dewi Melani Hariyadi, Noorma Rosita , 2018, Partition Coefficient and Glutathione Penetration of Topical Antiaging:Preformulation Study , International Journal of DrugDeliveryTechnology, ISSN 09754415; 8(2),39-43.https://www.scopus.com/inward/record.uri?eid=2-s2.0-85050701761&partnerID=40&md5=1d828e6e30958ca3058ab87850c0247f
12. Dewi Melani Hariyadi, Esti Hendradi, Tristiana Erawati, Edlin Nur Jannah, Wenny Febrina, 2018, Influence of Drug-Polymer Ratio on The Physical Characteristics and Release of Metformin HCl-Alginate Microspheres Concentration of Drug And Alginate Polymer, Tropical Journal of Pharmaceutical Research, ISSN 15965996; 17 (7), 1229-123. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85051111590&doi=10.4314%2ftjpr.v17i7.1&partnerID=40&md5=fe78bdcdd29012528dd1ef55d9fb2073
13. Dewi Melani Hariyadi, Noorma Rosita, Fitria Nugrahaeni, 2018, Formulation, Characteristic Evaluation, Stress Test and Effectiveness Study of Matrix Metalloproteinase-1 (MMP-1) Expression of Glutathione Loaded Alginate Microspheres and Gel, Pharmaceutical Sciences, ISSN 23832886; 24 (4): 304-312. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85060024188&doi=10.15171%2fPS.2018.44&partnerID=40&md5=c18c2de39135e0623c9411284d70b27b
14. Dewi M. Hariyadi, Tutiek Purwanti, Safira Adilla, 2018, Influence of Crosslinker Concentration on The Characteristics of Erythropoietin-Alginate Microspheres, Journal of Pharmacy andPharmacognosyResearch,ISSN 07194250; 6(4),250-259. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85049625193&partnerID=40&md5=1051846748f4a522d88d4cf033a94635
15. Dewi Melani Hariyadi, Mahardian Rahmad, Zakaria R, 2018, In Vivo Neuroprotectant Activity of Erythropoietin-Alginate Microspheres at Different Polymer Concentrations, Asian Journal of Pharmaceutics, ISSN 1998409X; 12(4), 255-260. https://www.asiapharmaceutics.info/index.php/ajp/article/view/2833/1027
16. Dewi Melani Hariyadi, Tristiana Erawati, Vita Fitria Ramadhani, 2019, Experimental Design Approach in Erythropoietin-alginate Microspheres Preparation with Different Concentration of Drug and Polymer, Journal of Report in Pharmaceutical Sciences, ISSN: 2322-5106; 8(1): 78-84. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85063739441&doi=10.4103%2fjrptps.jrptps_4_18&partnerID=40&md5=bdd8a4f1e95fd5b695e7d30dddb45ff2
17. Dewi Melani Hariyadi, Noorma Rosita, Isnaeni, Sisunandar Sudarma, Deavisca Rezania, 2022, Virgin Coconut Oil Emulgel: Effect of VCO and Carbopol 940 Concentration on Characterization and Antibacterial Activity, Research Journal of Pharmacy and Technology, 15(5), DOI: 10.52711/0974-360X.2022.00345
18. Noorma Rosita, Angguni Addini Sultani, Dewi Melani Hariyadi, 2022, Penetration study of p-methoxycinnamic acid (PMCA) in nanostructured lipid carrier, solid lipid nanoparticles, and simple cream into the rat skin, Scientific Reports, 12, Article number: 19365, https://doi.org/10.1038/s41598-022-23514-0
19. Rosita, Noorma; Ambarwati, Nadya; Erawati, Tristiana; Hariyadi, Dewi Melani, Characterization and in vitro release of inhalation quercetin solid lipid microparticles: Effect of lipid, Journal of Advanced Pharmaceutical Technology and Research,
    13(1):11-17.
20. Retno Widyowati, Suciati, Dewi M Hariyadi, HSin-I Chang, Ngurah IPG Suryawan, Nurliana Tarigan, Irawati Sholikhah, Chrismawan Ardianto, Ahmad D Nurhan, Ilham B Sagitaras, The pro-inflammatory cytokine IL-I? alteration by deer (Rusa unicolor) antler extract on osteoarthritis rat model, Saudi Pharmaceutical Journal, Volume 31, Issue 6, Pages 1109-1114
21. Andang Miatmoko, Berlian Sarasitha Hariawan, Devy Maulidya Cahyani, Syarifah Sutra Dewangga, Kevin Ksatria Handoko, Purwati, Ram Kumar Sahu & Dewi Melani Hariyadi, Prospective use of amniotic mesenchymal stem cell metabolite products for tissue regeneration, Journal of Biological Engineering, volume 17, Article number: 11.

Contact

Prof. apt., Dewi Melani Hariyadi, SSi, MPhil, PhD

E-mail dewiffua96@yahoo.com

E-mail instansi dewi-m-h@ff.unair.ac.id